Addiction


Addiction manifests itself through disruptions and enhancements of normal brain function. Current research focuses on the VTA-Accumbens-Cortex reward network. Informed Simplifications is creating quantitative models that will be useful for treating drug addiction.

Some brain regions required for cocaine-induced reinstatement
Some brain regions required for stress-induced reinstatement
Subcortical glutamatergic excitory inputs to the VTA and some co-transmitters.
Subcortical inhibitory inputs to the VTA. Co-transmitters include glutamate.